Dry eye · eye drops
There is no single best drop. There is a best drop for your kind of dry eye, and many people are using the wrong kind. How to choose from a pharmacy shelf, how to use them, and when drops are not the answer.
By Sohail Khan, Optometrist and Director, who has dry eye himself · Checked by Abra Arshad, Optometrist and Clinical Director · Updated 13 October 2026 · 11 min read
The best eye drop for dry eyes depends on why your eyes are dry. For most people the problem is a missing oil layer, so a drop or spray that adds oil helps more than a watery one. For eyes that don’t make enough tears, a longer-lasting lubricant such as hyaluronate suits better, with a gel or ointment at night. Choose preservative-free if you use drops more than four times a day. If you need drops more than six to eight times a day, the cause needs treating, not just the symptom.
Your tear film has three layers. A thin layer of mucus helps the tears stick to the eye. A watery layer, made by the tear glands, keeps the surface wet. On top is a very thin layer of oil from the glands in your eyelids, which stops the water evaporating between blinks.
Dry eye comes in two main types, and most people have some of both:
The drop that helps one type does much less for the other. That is why so many people say “I’ve tried every drop and none of them work”: they have usually tried several of the same kind. If you aren’t sure what is behind yours, what causes dry eyes explains the main reasons, most common first.
Pharmacy shelves look confusing, but almost every product is one of these. Look at the ingredients on the box rather than the brand name.
| Type | Common ingredients | Best for |
|---|---|---|
| Simple watery drops | Hypromellose, carmellose, polyvinyl alcohol | Mild, occasional dryness. Cheap, but wear off quickly |
| Longer-lasting drops | Sodium hyaluronate (hyaluronic acid), sometimes with trehalose | Everyday dryness and low tear volume. Cling to the eye for longer |
| Oil-based drops and sprays | Lipid emulsions, liposomal sprays, perfluorohexyloctane | Evaporative dry eye and blocked oil glands, which is most dry eye |
| Gels | Carbomer | Longer relief; blur the vision for a few minutes |
| Night ointments | Paraffin-based | Bedtime only, especially for eyes that are worst on waking |
Give any new drop two to three weeks, used regularly, before you judge it. Dry eye changes from day to day, so one good or bad day tells you little.
Preservatives stop bacteria growing in a multi-use bottle once it is open. The problem is that some preservatives, especially one called benzalkonium chloride, irritate the surface of the eye when used often. That is the opposite of what a dry eye needs.
The rule we give patients: if you use drops more than four times a day, use preservative-free. Many are now in multi-dose bottles with a special valve, so they don’t have to be single-use vials. If you use drops for something else as well, for example glaucoma drops, ask your optometrist or GP before adding anything.
If you wear contact lenses, use only drops that say on the box they are suitable for use with lenses. These are often sold as “rewetting” or “comfort” drops. Most are preservative-free, watery or hyaluronate drops.
A red, painful eye while wearing lenses is not a job for drops. Take the lens out, leave it out, and get seen the same day.
Some drops sold for “tired, red eyes” contain a decongestant that shrinks the small blood vessels on the eye so it looks whiter. They work for a few hours, but used regularly the eyes can turn redder when they wear off, so you use more. They do nothing for dryness.
If your eyes are red because they are dry, a good lubricant usually brings the redness down on its own. If redness is new, in one eye, painful or with blurred vision, don’t mask it with drops: see red eye: when to worry. Red, crusty lid edges are usually blepharitis, which drops alone won’t settle.
Every treatment starts with a free consultation with one of our optometrists, in person or on the phone. We talk through what you have tried, which type of dry eye it sounds like, and if treatment isn’t right for you, we say so before anything starts.
I have dry eye myself. It is the reason I stopped wearing contact lenses, and the reason laser eye surgery was never an option for me. I have stood in front of the same pharmacy shelf as everyone else.
What changed things for me was understanding that a drop does the job your tears should be doing, for as long as it lasts. If you need it every hour, the drop isn’t failing. It is telling you the cause hasn’t been dealt with.
Most people put drops in too quickly and lose half of them down the cheek. This way more of each drop stays on the eye:
Sprays that go on closed lids are different: follow the instructions on the box, usually held about 10 cm from closed eyes.
For mild dry eye, the NHS expects most people to buy lubricants from a pharmacy, and many GPs won’t prescribe them. For dry eye that stays severe despite good lubricants and lid care, doctors have other options. These are prescribed by a GP or, more often, started by an eye specialist:
We don’t prescribe ourselves, but if we think you need a prescription treatment we can write to your GP with what we have found.
Drops sit on top of the eye. If the cause is blocked oil glands or inflamed lids, the drop is standing in for the oil for half an hour, then evaporating. That is why so many people end up using drops eight or ten times a day and still feel gritty.
Signs it is time to treat the cause:
Warmth and lid care at home come first: see how to do a warm compress properly. When glands stay blocked, they can be cleared in clinic: MGD treatment explains how. For eyes that simply don’t make enough tears, tiny plugs can keep your own tears on the eye for longer. Every treatment and its price is on our dry eye clinic page.
Call any of our practices for an urgent appointment, or NHS 111. If it is severe and you can’t reach anyone, go to A&E. The full list is in our urgent eye signs.
When you don’t need us: if a preservative-free drop a few times a day keeps you comfortable, and your eyes are fine most of the time, carry on. That is what drops are for.
When it is worth coming in: if you are reaching for drops all day, have tried several kinds without much change, or your eyes are getting worse year on year.
There is no single best one. For gritty, burning eyes that are worse on screens, an oil-based drop or spray usually helps most. For eyes that feel dry all day, a preservative-free hyaluronate drop. A gel or ointment at night if your eyes are worst on waking.
Preservative-free lubricants can be used as often as you need. If you need them more than six to eight times a day, or they last less than an hour, the cause needs looking at rather than more drops.
Only drops labelled as suitable for contact lenses, usually preservative-free watery or hyaluronate drops. Put gels, ointments and most oil-based drops in before lenses go in or after they come out.
Preservative-free lubricants are very safe, even used often. Drops with preservatives can irritate the eye if used more than about four times a day, and redness-relief drops can make eyes redder with regular use.
For mild dry eye, usually not: the NHS expects lubricants to be bought from a pharmacy. For severe or inflamed dry eye, a GP or eye specialist may prescribe stronger treatments such as ciclosporin.
Most people start with EyeRelief, and it starts with a free consultation, at any of our five practices: Cheadle, Heald Green, Middleton, Winsford and Heckmondwike. No referral needed.